ABSTRACT
Aim: The aim of this study was to investigate the anti-fungal activity of Morinda citrifolia fruit extract on Candida albicans. Materials and Methods: Juice extract from M. citrifolia fruit was lyophilized and used in anti-fungal testing. Anti-fungal activity of M. citrifolia fruit extract against C. albicans was tested in vitro at various concentrations. The inhibitory effect of M. citrifolia extract on C. albicans was determined by agar culture and applied broth dilution test. Results: M. citrifolia extract at 1000 μg/ml concentration effectively inhibited the growth of C. albicans (16.6 ± 0.3) compared with the positive control - amphotericin B (20.6 ± 0.6). It was found to be a dose-dependent reaction. Conclusion: M. citrifolia fruit extract had an anti-fungal effect on C. albicans and the inhibitory effect varied with concentration.
Subject(s)
Antifungal Agents , Candida albicans/drug effects , In Vitro Techniques , Morinda/therapeutic use , Plant Extracts/therapeutic useABSTRACT
Aim: This study aims to investigate oral hygiene and frequency of oral cleaning in children up to 5 years in relation to mother related factors. Materials and Methods: A cross-sectional study of 250 children aged 1-5 years in Chennai, Tamil Nadu was implemented. Mothers answered questions about their own oral self-care and their children’s oral hygiene. Chi-square test and logistic regression analysis was done. Results: Twice daily oral cleaning was reported for 95% of all children . 92% of the mothers believed it necessary to rinse the mouth between meals and to clean the gum pads even if teeth have not erupted. Oral hygiene was seen to be better in children whose mother’s own brushing frequency was high. It was also seen that mothers with a higher educational level had a better attitude towards their child’s oral hygiene care. Conclusion: To improve oral hygiene in early childhood, more emphasis should be placed on mother’s own tooth brushing practice and their skills in their children’s oral hygiene.